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Difference between Differ from someone and Differ with someone

differ from someone

1. be unlike another person in some way:

  • John only differs from his brother in being less masculine and less sternly religious.

2. have different opinions on some matter:

  • My dear sir, I am sorry to differ from you. I think that we are soldiers, and damned good ones at that.

differ with someone — = differ from someone 2:

  • In politics, he differed with his brother-in-law, William Biles, Hough adhering strongly to the Proprietary party.