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Work at something vs Work on something

work at somethingbe busy or occupied with smth.; apply one’s efforts to smth.:

  • Is Tom still working at the new book that he promised?

work on something

1. = work at something:

  • I’m presently working on the new book, another suspense novel, after which I plan to write a book for aspiring writers.

2. influence smth.; have an effect on smth.:

  • Acebutolol is taken orally so that it works on the central nervous system of those prone to heart attacks.