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Difference between Be one too many and Have one too many

be one too many —(coll.) be more than a match for a person:

  • I venture to prophesy that, between us, we shall be one too many for the Colonel.

have one too many —(coll.) take more alcohol than one can drink:

  • The man was a little tipsy; it looked like he had had one too many for complete control of his faculties.