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Difference between Be off one’s nut and Get one’s nuts off

be off one’s nut—(sl.) be out of one’s mind; be insane:

  • But is the master off his nut that he has her down here to stay?

get one’s nuts off—(coarse sl.) obtain sexual release:

  • Screwin’ my white friend’s black wife makes me feel even better. Makes me get my nuts off.